Chagas Disease Diagnostic Practices at Four Major Hospital Systems in California and Texas.
J Infect Dis
; 229(1): 198-202, 2024 Jan 12.
Article
em En
| MEDLINE
| ID: mdl-37853514
ABSTRACT
BACKGROUND:
Chagas disease (CD) is a parasitic disease that affects â¼300 000 people living in the United States. CD leads to cardiac and/or gastrointestinal disease in up to 30% of untreated people. However, end-organ damage can be prevented with early diagnosis and antiparasitic therapy.METHODS:
We reviewed electronic health records of patients who underwent testing for CD at four hospital systems in California and Texas between 2016 and 2020. Descriptive analyses were performed as a needs assessment for improving CD diagnosis.RESULTS:
In total, 470 patients were tested for CD. Cardiac indications made up more than half (60%) of all testing, and the most frequently cited cardiac condition was heart failure. Fewer than 1% of tests were ordered by obstetric and gynecologic services. Fewer than half (47%) of patients had confirmatory testing performed at the Centers for Disease Control and Prevention.DISCUSSION:
Four major hospitals systems in California and Texas demonstrated low overall rates of CD diagnostic testing, testing primarily among older patients with end-organ damage, and incomplete confirmatory testing. This suggests missed opportunities to diagnose CD in at-risk individuals early in the course of infection when antiparasitic treatment can reduce the risk of disease progression and prevent vertical transmission.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Trypanosoma cruzi
/
Doença de Chagas
Limite:
Female
/
Humans
/
Pregnancy
País/Região como assunto:
America do norte
Idioma:
En
Revista:
J Infect Dis
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos