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Coronary arterial repair in patients with stable angina pectoris or acute coronary syndrome after ultrathin biodegradable polymer sirolimus-eluting stent implantation at 1-year follow-up by coronary angioscopy.
Ichikawa, Minoru; Matsuoka, Yuki; Hasebe, Terumitsu.
Afiliação
  • Ichikawa M; Department of Cardiology, Higashi-Osaka City Medical Center, Osaka, Japan.
  • Matsuoka Y; Department of Cardiology, Higashi-Osaka City Medical Center, Osaka, Japan.
  • Hasebe T; Department of Radiology, Tokai University School of Medicine, Kanagawa, Japan.
Catheter Cardiovasc Interv ; 102(6): 1012-1019, 2023 11.
Article em En | MEDLINE | ID: mdl-37925619
BACKGROUND: Imaging modality-based evidence is limited that compares the extent of coronary arterial repair after percutaneous coronary intervention between patients with stable angina pectoris (SAP) and those with acute coronary syndrome (ACS). METHODS: Between December 2018 and November 2021, a single-center, nonrandomized, observational study was conducted in 92 patients with SAP (n = 42) or ACS (n = 50), who were implanted with Orsiro sirolimus-eluting stent (O-SES) providing a hybrid (active and passive) coating and underwent 1-year follow-up by coronary angioscopy (CAS) after implantation. CAS assessed neointimal coverage (NIC), maximum yellow plaque (YP), and mural thrombus (MT). RESULTS: Baseline clinical characteristics were comparable between the SAP and ACS groups. The follow-up periods were comparable between the two groups (390.1 ± 69.9 vs. 390.6 ± 65.7 days, p = 0.99). The incidences of MT at 1 year after implantation were comparable between the two groups (11.4% vs. 11.1%, p = 0.92). The proportions of "Grade 1" in dominant NIC grades were highest in both groups, and the proportions of maximum YP grades and MT were comparable between the two groups. CONCLUSION: O-SES-induced coronary arterial repair at the site of stent implantation, irrespective of the types of coronary artery disease.
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Trombose / Doença da Artéria Coronariana / Síndrome Coronariana Aguda / Stents Farmacológicos / Angina Estável / Intervenção Coronária Percutânea Limite: Humans Idioma: En Revista: Catheter Cardiovasc Interv Assunto da revista: CARDIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Trombose / Doença da Artéria Coronariana / Síndrome Coronariana Aguda / Stents Farmacológicos / Angina Estável / Intervenção Coronária Percutânea Limite: Humans Idioma: En Revista: Catheter Cardiovasc Interv Assunto da revista: CARDIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão