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An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant.
Mende, Hannah; Khatri, Anshu; Lange, Carolin; Poveda-Cuevas, Sergio Alejandro; Tascher, Georg; Covarrubias-Pinto, Adriana; Löhr, Frank; Koschade, Sebastian E; Dikic, Ivan; Münch, Christian; Bremm, Anja; Brunetti, Lorenzo; Brandts, Christian H; Uckelmann, Hannah; Dötsch, Volker; Rogov, Vladimir V; Bhaskara, Ramachandra M; Müller, Stefan.
Afiliação
  • Mende H; Goethe University Frankfurt, Institute of Biochemistry II, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Khatri A; Goethe University Frankfurt, Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Max-von-Laue Street 9, 60438 Frankfurt, Germany.
  • Lange C; Goethe University Frankfurt, Institute of Biochemistry II, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany; Goethe University Frankfurt, Buchmann Institute for Molecular Life Sciences, Max-von-Laue Street 15, 60438 Frankfurt, Germany.
  • Poveda-Cuevas SA; Goethe University Frankfurt, Institute of Biochemistry II, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany; Goethe University Frankfurt, Buchmann Institute for Molecular Life Sciences, Max-von-Laue Street 15, 60438 Frankfurt, Germany.
  • Tascher G; Goethe University Frankfurt, Institute of Biochemistry II, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Covarrubias-Pinto A; Goethe University Frankfurt, Institute of Biochemistry II, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Löhr F; Goethe University Frankfurt, Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Max-von-Laue Street 9, 60438 Frankfurt, Germany.
  • Koschade SE; Goethe University Frankfurt, Institute of Biochemistry II, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany; Goethe University Frankfurt, University Hospital, Department of Medicine, Hematology/Oncology, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Dikic I; Goethe University Frankfurt, Institute of Biochemistry II, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Münch C; Goethe University Frankfurt, Institute of Biochemistry II, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Bremm A; Goethe University Frankfurt, Institute of Biochemistry II, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Brunetti L; Marche Polytechnic University, Department of Clinical and Molecular Sciences, Via Tronto 10, 60020 Ancona, Italy.
  • Brandts CH; Goethe University Frankfurt, University Hospital, Department of Medicine, Hematology/Oncology, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Uckelmann H; Goethe University Frankfurt, University Hospital, Department of Pediatrics, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Dötsch V; Goethe University Frankfurt, Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Max-von-Laue Street 9, 60438 Frankfurt, Germany.
  • Rogov VV; Goethe University Frankfurt, Institute of Pharmaceutical Chemistry, Max-von-Laue Street 15, 60438 Frankfurt, Germany; Goethe University Frankfurt, Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences, Max-von-Laue Street 15, 60438 Frankfurt, Germany.
  • Bhaskara RM; Goethe University Frankfurt, Institute of Biochemistry II, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany; Goethe University Frankfurt, Buchmann Institute for Molecular Life Sciences, Max-von-Laue Street 15, 60438 Frankfurt, Germany. Electronic address: bhaskara@med.uni-frankfurt.de.
  • Müller S; Goethe University Frankfurt, Institute of Biochemistry II, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany. Electronic address: ste.mueller@em.uni-frankfurt.de.
Cell Rep ; 42(12): 113484, 2023 12 26.
Article em En | MEDLINE | ID: mdl-37999976
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Proteínas Nucleares / Leucemia Mieloide Aguda Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Proteínas Nucleares / Leucemia Mieloide Aguda Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha