Development of Novel Epigenetic Anti-Cancer Therapy Targeting TET Proteins.

Kim, Hyejin; Jung, Inkyung; Lee, Chan Hyeong; An, Jungeun; Ko, Myunggon

Kim, Hyejin; Jung, Inkyung; Lee, Chan Hyeong; An, Jungeun; Ko, Myunggon.

Afiliação

Kim H; Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
Jung I; Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
Lee CH; Department of Life Sciences, Jeonbuk National University, Jeonju 54896, Republic of Korea.
An J; Department of Life Sciences, Jeonbuk National University, Jeonju 54896, Republic of Korea.
Ko M; Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.

Int J Mol Sci ; 24(22)2023 Nov 15.

Article em En | MEDLINE | ID: mdl-38003566

Assuntos

Dioxigenases; Leucemia; Neoplasias; Animais; Camundongos; Mitoxantrona; Proteínas de Ligação a DNA/genética; Proteínas de Ligação a DNA/metabolismo; Fibroblastos/metabolismo; Neoplasias/tratamento farmacológico; Neoplasias/genética; Neoplasias/metabolismo; Metilação de DNA; 5-Metilcitosina/metabolismo; Epigênese Genética; Leucemia/genética; Dioxigenases/genética

Palavras-chave

DNA methylation; TET proteins; cancer therapy; cell-based screening; epigenetic dysregulation; hydroxymethylation; mitoxantrone

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Leucemia / Dioxigenases / Neoplasias Limite: Animals Idioma: En Revista: Int J Mol Sci Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google