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A novel scaffold long-acting selective estrogen receptor antagonist and degrader with superior preclinical profile against ER+ breast cancer.
Wang, Bingsi; Ma, Mingxu; Dai, Yusen; Yu, Pengfei; Ye, Liang; Wang, Wenyan; Sha, Chunjie; Yang, Huijie; Yang, Yingjie; Zhu, Yunjing; Dong, Lin; Wei, Shujuan; Wang, Linlin; Tian, Jingwei; Wang, Hongbo.
Afiliação
  • Wang B; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, China.
  • Ma M; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, China.
  • Dai Y; R & D Center, Luye Pharma Group Ltd., Yantai, 264003, China.
  • Yu P; School of Pharmacy, Binzhou Medical University, Yantai, China.
  • Ye L; School of Pharmacy, Binzhou Medical University, Yantai, China.
  • Wang W; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, China.
  • Sha C; R & D Center, Luye Pharma Group Ltd., Yantai, 264003, China.
  • Yang H; R & D Center, Luye Pharma Group Ltd., Yantai, 264003, China.
  • Yang Y; R & D Center, Luye Pharma Group Ltd., Yantai, 264003, China.
  • Zhu Y; R & D Center, Luye Pharma Group Ltd., Yantai, 264003, China.
  • Dong L; R & D Center, Luye Pharma Group Ltd., Yantai, 264003, China.
  • Wei S; R & D Center, Luye Pharma Group Ltd., Yantai, 264003, China.
  • Wang L; Department of Food Engineering, Shandong Business Institute, Yantai, 264670, China. Electronic address: wanglinlin@sdbi.edu.cn.
  • Tian J; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, China. Electronic address: T
  • Wang H; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, China. Electronic address: h
Eur J Med Chem ; 264: 115934, 2024 Jan 15.
Article em En | MEDLINE | ID: mdl-38007911
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias da Mama Limite: Female / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias da Mama Limite: Female / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China