Directed Evolution of Genetically Encoded LYTACs for Cell-Mediated Delivery.

Yang, Jonathan Lee; Yamada-Hunter, Sean A; Labanieh, Louai; Sotillo, Elena; Cheah, Joleen S; Roberts, David S; Mackall, Crystal L; Ting, Alice Y; Bertozzi, Carolyn R

Yang, Jonathan Lee; Yamada-Hunter, Sean A; Labanieh, Louai; Sotillo, Elena; Cheah, Joleen S; Roberts, David S; Mackall, Crystal L; Ting, Alice Y; Bertozzi, Carolyn R.

Afiliação

Yang JL; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
Yamada-Hunter SA; Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Labanieh L; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Sotillo E; Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Cheah JS; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Roberts DS; Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Mackall CL; Departments of Biology, and Genetics Stanford University, Stanford, CA 94305, USA.
Ting AY; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
Bertozzi CR; Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

bioRxiv ; 2023 Nov 15.

Article em En | MEDLINE | ID: mdl-38014030

Palavras-chave

Cell therapy; Chemical biology; Targeted protein degradation; synthetic biology

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos