Suppressing DNMT3a Alleviates the Intrinsic Epigenetic Barrier for Optic Nerve Regeneration and Restores Vision in Adult Mice.

Tai, Wai Lydia; Cho, Kin-Sang; Kriukov, Emil; Ashok, Ajay; Wang, Xuejian; Monavarfeshani, Aboozar; Yan, Wenjun; Li, Yingqian; Guan, Timothy; Sanes, Joshua R; Baranov, Petr; Chen, Dong Feng

Tai, Wai Lydia; Cho, Kin-Sang; Kriukov, Emil; Ashok, Ajay; Wang, Xuejian; Monavarfeshani, Aboozar; Yan, Wenjun; Li, Yingqian; Guan, Timothy; Sanes, Joshua R; Baranov, Petr; Chen, Dong Feng.

Afiliação

Tai WL; Schepens Eye Research Institute of Mass Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Cho KS; Schepens Eye Research Institute of Mass Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Kriukov E; Schepens Eye Research Institute of Mass Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Ashok A; Schepens Eye Research Institute of Mass Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Wang X; Schepens Eye Research Institute of Mass Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Monavarfeshani A; School of Pharmacy, Weifang Medical University, Weifang, Shandong, China.
Yan W; Department of Cellular and Molecular Biology, Center for Brain Science, Harvard University, MA, USA.
Li Y; Department of Cellular and Molecular Biology, Center for Brain Science, Harvard University, MA, USA.
Guan T; Schepens Eye Research Institute of Mass Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Sanes JR; Schepens Eye Research Institute of Mass Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Baranov P; Department of Cellular and Molecular Biology, Center for Brain Science, Harvard University, MA, USA.
Chen DF; Schepens Eye Research Institute of Mass Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.

bioRxiv ; 2023 Nov 23.

Article em En | MEDLINE | ID: mdl-38014168

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos