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A randomised phase 2 study of intermittent versus continuous dosing of dabrafenib plus trametinib in patients with BRAFV600 mutant advanced melanoma (INTERIM).
Dayimu, Alimu; Gupta, Avinash; Matin, Rubeta N; Nobes, Jenny; Board, Ruth; Payne, Miranda; Rao, Ankit; Fusi, Alberto; Danson, Sarah; Eccles, Bryony; Carser, Judith; Brown, Ciara O'Hanlon; Steven, Neil; Bhattacharyya, Madhumita; Brown, Ewan; Gonzalez, Michael; Highley, Martin; Pickering, Lisa; Kumar, Satish; Waterston, Ashita; Burghel, George; Demain, Leigh; Baker, Eleanor; Wulff, Jerome; Qian, Wendi; Twelves, Sophie; Middleton, Mark; Corrie, Pippa.
Afiliação
  • Dayimu A; Clinical Trials Unit, Department of Oncology, University of Cambridge, Cambridge, UK.
  • Gupta A; The Christie NHS Foundation Trust, Manchester, UK.
  • Matin RN; Department of Dermatology, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
  • Nobes J; Department of Oncology, Norfolk and Norwich University Hospital NHS Foundation Trust, Norfolk, UK.
  • Board R; Department of Oncology, Lancashire Teaching Hospitals NHS Trust, Preston, UK.
  • Payne M; Oxford Cancer and Haematology Centre, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK.
  • Rao A; Department of Oncology, Nottingham University Hospitals NHS Trust, Nottingham, UK.
  • Fusi A; Department of Medical Oncology, St George's University Hospitals NHS Foundation Trust, London, UK.
  • Danson S; Division of Clinical Medicine, The University of Sheffield, Sheffield, UK; Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK.
  • Eccles B; Department of Medical Oncology, University Hospitals Dorset NHS Foundation Trust, Poole, UK.
  • Carser J; Department of Oncology, Belfast Health and Social Care Trust, Belfast, UK.
  • Brown CO; St James's Hospital, Dublin, Ireland.
  • Steven N; Department of Oncology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
  • Bhattacharyya M; Department of Oncology, Royal Berkshire NHS Foundation Trust, Reading, UK.
  • Brown E; Western General Hospital, Lothian NHS Board, Edinburgh, UK.
  • Gonzalez M; Department of Oncology, Imperial College Healthcare NHS Trust, London, UK.
  • Highley M; Oncology Centre, Derriford Hospital, University Hospitals Plymouth NHS Trust, Plymouth, UK.
  • Pickering L; Skin and Renal Units, Royal Marsden NHS Foundation Trust, London, UK.
  • Kumar S; Velindre Cancer Centre, Velindre University NHS Trust, Cardiff, UK.
  • Waterston A; Beatson West of Scotland Cancer Centre, Glasgow, UK.
  • Burghel G; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK.
  • Demain L; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK.
  • Baker E; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK.
  • Wulff J; Cambridge Clinical Trials Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Qian W; Clinical Trials Unit, Department of Oncology, University of Cambridge, Cambridge, UK; Cambridge Clinical Trials Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Twelves S; Cambridge Clinical Trials Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Middleton M; Oxford Cancer and Haematology Centre, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK; Department of Oncology, University of Oxford, Oxford, UK.
  • Corrie P; Oncology Department, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. Electronic address: philippa.corrie@nhs.net.
Eur J Cancer ; 196: 113455, 2024 Jan.
Article em En | MEDLINE | ID: mdl-38029480
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Melanoma Limite: Aged / Humans Idioma: En Revista: Eur J Cancer Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Melanoma Limite: Aged / Humans Idioma: En Revista: Eur J Cancer Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Reino Unido