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Combinatorial design of ionizable lipid nanoparticles for muscle-selective mRNA delivery with minimized off-target effects.
Chen, Jingan; Xu, Yue; Zhou, Muye; Xu, Shufen; Varley, Andrew James; Golubovic, Alex; Lu, Rick Xing Ze; Wang, Kevin Chang; Yeganeh, Mina; Vosoughi, Daniel; Li, Bowen.
Afiliação
  • Chen J; Institute of Biomedical Engineering, University of Toronto, Toronto, ON M5S 3G9, Canada.
  • Xu Y; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada.
  • Zhou M; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada.
  • Xu S; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada.
  • Varley AJ; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada.
  • Golubovic A; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada.
  • Lu RXZ; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada.
  • Wang KC; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada.
  • Yeganeh M; Institute of Medical Science, University of Toronto, Toronto, ON M5G 1L7, Canada.
  • Vosoughi D; Institute of Medical Science, University of Toronto, Toronto, ON M5G 1L7, Canada.
  • Li B; Latner Thoracic Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, ON M5G 2C4, Canada.
Proc Natl Acad Sci U S A ; 120(50): e2309472120, 2023 Dec 12.
Article em En | MEDLINE | ID: mdl-38060560
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Nanopartículas / Vacinas de mRNA Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Nanopartículas / Vacinas de mRNA Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá