Association between Cesarean section delivery and increased risk of childhood Kawasaki disease.
J Formos Med Assoc
; 2023 Dec 14.
Article
em En
| MEDLINE
| ID: mdl-38097429
ABSTRACT
AIM:
Cesarean section delivery is associated with microbiota disruption and immuno-dysregulation during childhood, but the association with Kawasaki disease remains uncertain. We aimed to evaluate the association between Cesarean section and Kawasaki disease.METHODS:
We examined the association between Kawasaki disease between six and eighteen months and Cesarean section within a birth cohort of 15,796 mother-infant pairs in Taiwan. The associations were assessed with Poisson regression in the study population, in the 12 propensity score-matched subpopulation, and compared with febrile convulsion, trauma and accidents during the same interval as negative control outcomes.RESULTS:
Cesarean section was found to increase the risk of Kawasaki disease among overall population (adjusted relative risk [aRR] 2.22, 95 % confidence interval (CI) 1.14-4.34) and the matched subpopulation (aRR 2.29, 95 % CI 1.14-4.68 in PS-matched subpopulation). Meanwhile, there was no association between Cesarean section and the clinic visits for febrile convulsion, trauma and accidents.CONCLUSION:
In conclusion, this study identified a potential association between Cesarean section delivery and a higher risk of Kawasaki disease during six-to eighteen months of the prospective birth cohort in Taiwan.
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Bases de dados:
MEDLINE
Idioma:
En
Revista:
J Formos Med Assoc
Assunto da revista:
MEDICINA
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Estados Unidos