Long-term outcomes of patients with oral cavity cancer receiving postoperative radiotherapy after salvage neck dissection for cervical lymph node recurrence.
Head Neck
; 46(3): 541-551, 2024 03.
Article
em En
| MEDLINE
| ID: mdl-38108511
ABSTRACT
BACKGROUNDS We aimed to clarify the outcomes of postoperative radiotherapy (PORT) after salvage neck dissection for cervical lymph node (LN) recurrence in oral cavity cancer. METHODS:
We retrospectively evaluated overall survival (OS), recurrence-free survival (RFS), recurrence patterns, and adverse events of 51 patients with high-risk features receiving PORT after salvage neck dissection between 2009 and 2019.RESULTS:
After a median follow-up of 7.4 years from PORT initiation, the 7-year OS and RFS rates were 66.3% (95% CI 54.0-81.3) and 54.6% (95% CI 42.1-70.9), respectively. Age <70 years and isolated LN recurrence were significantly associated with longer OS and RFS. Among the 22 patients who experienced recurrence, 14 experienced recurrence within the radiation field. PORT-related grade 3 acute mucositis (35%) and late adverse events (osteoradionecrosis [4%] and laryngeal stenosis [2%]) were observed.CONCLUSIONS:
PORT after salvage neck dissection for cervical LN recurrence achieved good survival with acceptable toxicity.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Esvaziamento Cervical
/
Neoplasias Bucais
Limite:
Aged
/
Humans
Idioma:
En
Revista:
Head Neck
Assunto da revista:
NEOPLASIAS
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Japão