Fast and efficient size exclusion chromatography of adeno associated viral vectors with 2.5 micrometer particle low adsorption columns.

Imiolek, Mateusz; Fekete, Szabolcs; Kizekai, Lavelay; Addepalli, Balasubrahmanyam; Lauber, Matthew

Imiolek, Mateusz; Fekete, Szabolcs; Kizekai, Lavelay; Addepalli, Balasubrahmanyam; Lauber, Matthew.

Afiliação

Imiolek M; Waters Corporation, 1 Rue Michel Servet, Geneva 1211, Switzerland. Electronic address: mateusz_imiolek@waters.com.
Fekete S; Waters Corporation, 1 Rue Michel Servet, Geneva 1211, Switzerland.
Kizekai L; Waters Corporation, 34 Maple Street, Milford MA 01757, United States of America.
Addepalli B; Waters Corporation, 34 Maple Street, Milford MA 01757, United States of America.
Lauber M; Waters Corporation, 34 Maple Street, Milford MA 01757, United States of America.

J Chromatogr A ; 1714: 464587, 2024 Jan 11.

Article em En | MEDLINE | ID: mdl-38150795

Assuntos

Adsorção; Reprodutibilidade dos Testes; Tamanho da Partícula; Cromatografia em Gel; Cinética

Palavras-chave

AAVs; Adeno associated virus; Gene therapy; SEC; Size exclusion chromatography; Size variants analysis

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Adsorção Idioma: En Revista: J Chromatogr A Ano de publicação: 2024 Tipo de documento: Article