[Analysis methods and case analysis of effect modification (1): effect modification in epidemiology and traditional Meta-analysis].
Zhonghua Liu Xing Bing Xue Za Zhi
; 45(1): 148-154, 2024 Jan 10.
Article
em Zh
| MEDLINE
| ID: mdl-38228538
ABSTRACT
This paper briefly introduces the definition, classification and significance of effect modification in epidemiological studies, summarizes the difference between effect modifier and confounders, and analyze the influence as well as the role of effect modification in epidemiological studies and Meta-analysis. In this paper, the possible scenarios of effect modification and related analysis strategy in Meta-analysis are indicated by graphics, aiming to arouse researchers' attention to effect modification. This paper also demonstrates how to identify and deal with effect modification in Meta-analysis through a study case of "Efficacy of sodium-glucose cotransporter 2 inhibitors in patients with type 2 diabetes", and shows the analysis process and interpretation of results of subgroup analysis and Meta-regression methods respectively. The advantages and disadvantages of these two methods are summarized to provide reference for the method selection of future research.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Diabetes Mellitus Tipo 2
Tipo de estudo:
Screening_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
Zh
Revista:
Zhonghua Liu Xing Bing Xue Za Zhi
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China