Mature cystic ovarian teratoma with squamous cell carcinoma transformation: a case report and literature review.
Horm Mol Biol Clin Investig
; 45(1): 35-39, 2024 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-38282269
ABSTRACT
OBJECTIVES:
Cancerous transformation in mature cystic ovarian teratoma is rare. Herein, we reported a case of squamous cell carcinoma transformation in mature cystic ovarian teratoma and performed an in-depth literature review to highlight the risk factors, prognosis, and suggested treatment for these patients. CASE PRESENTATION We report a 66-years old postmenopausal woman diagnosed with a 120×90â¯(mm) mass at the left adnexa compatible with mature cystic ovarian teratoma. Following resection, the histopathological investigations showed malignant transformation in her mature cystic ovarian teratoma, and the immunohistochemistry for cytokeratin (CK) 5/6 and tumor protein 63 (P63) indicated squamous cell carcinoma transformation. She has been observed for her stage IA tumor and has been cancer-free for 6 months.CONCLUSIONS:
Although malignant transformation in mature cystic ovarian teratoma is rare, it should be suspected if certain risk factors, e.g., elderly and high tumor size, exist. Stage IA patients' prognosis is favorable, and chemotherapy is not recommended.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Neoplasias Ovarianas
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Teratoma
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Carcinoma de Células Escamosas
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
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Female
/
Humans
Idioma:
En
Revista:
Horm Mol Biol Clin Investig
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Irã