Frequency of skin diseases in renal transplant recipients and patients with chronic kidney disease in a tertiary center: a cross-sectional study.
Sao Paulo Med J
; 142(4): 2023148, 2024.
Article
em En
| MEDLINE
| ID: mdl-38422240
ABSTRACT
BACKGROUND:
The prevalence of chronic kidney disease (CKD) has increased in the recent decades, along with the number of patients in the terminal stages of this disease, requiring transplantation. Some skin disorders are more frequent in patients with CKD and in renal transplant recipients (RTR).OBJECTIVES:
To evaluate the frequency of skin diseases in RTR and patients with CKD receiving conservative treatment. DESIGN ANDSETTING:
This observational cross-sectional study recruited consecutive patients with CKD and RTR from a nephrology clinic at a teaching hospital in Brazil between 2015 and 2020.METHODS:
Quantitative, descriptive, and analytical approaches were used. The sample was selected based on convenience sampling. Data were collected from dermatological visits and participants' medical records.RESULTS:
Overall, 308 participants were included 206 RTR (66.9%, median age 48 years, interquartile range [IQR] 38.0-56.0, 63.6% men) and 102 patients with CKD (33.1%, median age 61.0 years, IQR 50.0-71.2, 48% men). The frequency of infectious skin diseases (39.3% vs. 21.6% P = 0.002) were higher in RTR than in patients with CKD. Neoplastic skin lesions were present in nine (4.4%) RTR and in only one (1.0%) patient with CKD. Among the RTR, the ratio of basal cell carcinoma to squamous cell carcinoma was 21.CONCLUSIONS:
This study revealed that an increased frequency of infectious skin diseases may be expected in patients who have undergone kidney transplantation. Among skin cancers, BCC is more frequently observed in RTR, especially in those using azathioprine.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Dermatopatias
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Dermatopatias Infecciosas
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Transplante de Rim
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Insuficiência Renal Crônica
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Sao Paulo Med J
Assunto da revista:
MEDICINA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Brasil