[Progress in research on mRNA therapeutics for the treatment of genetic diseases].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
; 41(3): 368-376, 2024 Mar 10.
Article
em Zh
| MEDLINE
| ID: mdl-38448031
ABSTRACT
In recent years, mRNA drugs have shown a great potential for the treatment of genetic diseases and attracted the attention of many researchers. This article has reviewed the advance in the research of mRNA drugs for the treatment of genetic diseases over the past 30 years, including their mechanisms of action and structure design, with a focus on their advantages as alternative therapies such as high specificity, low dosage, and sustained expression. Meanwhile, challenges for the effective delivery and storage methods for the mRNA drugs are discussed, with an aim to provide guidance for subsequent researches.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
RNA Mensageiro
Limite:
Humans
Idioma:
Zh
Revista:
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
Assunto da revista:
GENETICA MEDICA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China