Bacterial diversity and chemical ecology of natural product-producing bacteria from Great Salt Lake sediment.
ISME Commun
; 4(1): ycae029, 2024 Jan.
Article
em En
| MEDLINE
| ID: mdl-38524762
ABSTRACT
Great Salt Lake (GSL), located northwest of Salt Lake City, UT, is the largest terminal lake in the USA. While the average salinity of seawater is ~3.3%, the salinity in GSL ranges between 5% and 28%. In addition to being a hypersaline environment, GSL also contains toxic concentrations of heavy metals, such as arsenic, mercury, and lead. The extreme environment of GSL makes it an intriguing subject of study, both for its unique microbiome and its potential to harbor novel natural product-producing bacteria, which could be used as resources for the discovery of biologically active compounds. Though work has been done to survey and catalog bacteria found in GSL, the Lake's microbiome is largely unexplored, and little to no work has been done to characterize the natural product potential of GSL microbes. Here, we investigate the bacterial diversity of two important regions within GSL, describe the first genomic characterization of Actinomycetota isolated from GSL sediment, including the identification of two new Actinomycetota species, and provide the first survey of the natural product potential of GSL bacteria.
Texto completo:
1
Bases de dados:
MEDLINE
Idioma:
En
Revista:
ISME Commun
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos