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Putting More Weight on Obesity Trials in Heart Failure.
Harrington, Josephine; Sattar, Naveed; Felker, G Michael; Januzzi, James L; Lam, Carolyn S P; Pagidipati, Neha J; Pandey, Ambarish; Van Spall, Harriette G C; McGuire, Darren K.
Afiliação
  • Harrington J; Division of Cardiology, Department of Internal Medicine, Duke University Medical Center, Durham, NC, USA. josephine.harrington@duke.edu.
  • Sattar N; Duke Clinical Research Institute, 300 W. Morris St, Durham, NC, 27701, USA. josephine.harrington@duke.edu.
  • Felker GM; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
  • Januzzi JL; Division of Cardiology, Department of Internal Medicine, Duke University Medical Center, Durham, NC, USA.
  • Lam CSP; Duke Clinical Research Institute, 300 W. Morris St, Durham, NC, 27701, USA.
  • Pagidipati NJ; Baim Institute for Clinical Research, Boston, MA, USA.
  • Pandey A; Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Van Spall HGC; Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • McGuire DK; National Heart Centre Singapore and Duke-National University of Singapore, Bukit Merah, Singapore.
Curr Heart Fail Rep ; 21(3): 194-202, 2024 06.
Article em En | MEDLINE | ID: mdl-38619690
ABSTRACT
PURPOSE OF REVIEW To review ongoing and planned clinical trials of weight loss among individuals with or at high risk of heart failure. RECENT

FINDINGS:

Intentional weight loss via semaglutide among persons with heart failure and preserved ejection fraction and obesity significantly improves weight loss and health status as assessed by the KCCQ-CSS score and is associated with improvements in 6-min walk test. Ongoing and planned trials will explore the role of intentional weight loss with treatments such as semaglutide or tirzepatide for individuals with heart failure across the entire ejection fraction spectrum.
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Redução de Peso / Insuficiência Cardíaca / Obesidade Limite: Humans Idioma: En Revista: Curr Heart Fail Rep Assunto da revista: CARDIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Redução de Peso / Insuficiência Cardíaca / Obesidade Limite: Humans Idioma: En Revista: Curr Heart Fail Rep Assunto da revista: CARDIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos