Prevalence of high-risk HPV and cervical dysplasia in IUD users and controls: a cross sectional study.
Eur J Contracept Reprod Health Care
; 29(3): 109-114, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38666336
ABSTRACT
OBJECTIVE:
To examine the prevalence of infections with high-risk human papillomavirus (HPV) and cervical dysplasia, and the clearance rate of HPV infections, in users of different kinds of intrauterine devices (IUDs) and other contraceptive methods.METHODS:
A cross-sectional register-based study including 16,181 women aged 30-49 years participating in the screening programme for cervical cancer in a Swedish County in 2017-2018. Data on contraception from screening records was paired with the HPV test results, cytological and histological follow-up tests and subsequent HPV test.RESULTS:
There was no difference in the risk of being HPV positive, or histological HSIL+, between users of copper-containing IUDs and women with no reported use of contraception. Use of levonorgestrel intrauterine system and hormonal contraception were associated with higher odds for HPV infection in age-adjusted models (aOR 1.21; 95% CI 1.04-1.41, and aOR 1.41; 95% CI 1.22-1.63, respectively) and for HSIL+ (aOR 1.45; 95% CI 1.02-2.06, and aOR 1.56; 95% CI 1.13-2.16, respectively). No significant differences were found in HPV clearance rates.CONCLUSIONS:
Reported use of levonorgestrel intrauterine system and hormonal contraception, but not use of copper IUD, was associated with a higher prevalence of HPV infections and histological HSIL + compared to no reported use of contraception.
Women using copper IUD showed no difference in prevalence of HPV or cervical dysplasia compared to women not using contraception in cross-sectional study.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Displasia do Colo do Útero
/
Infecções por Papillomavirus
/
Dispositivos Intrauterinos
Limite:
Adult
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Female
/
Humans
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Eur J Contracept Reprod Health Care
Assunto da revista:
MEDICINA REPRODUTIVA
/
SERVICOS DE PLANEJAMENTO FAMILIAR
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Suécia