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Applying 3D ED/MicroED workflows toward the next frontiers.
Aragon, Mahira; Bowman, Sarah E J; Chen, Chun Hsing; de la Cruz, M Jason; Decato, Daniel A; Eng, Edward T; Flatt, Kristen M; Gulati, Sahil; Li, Yuchen; Lomba, Charles J; Mercado, Brandon; Miller, Jessalyn; Palatinus, Lukás; Rice, William J; Waterman, David; Zimanyi, Christina M.
Afiliação
  • Aragon M; Simons Electron Microscopy Center, New York Structural Biology Center, 89 Convent Ave, New York, New York 10027, USA.
  • Bowman SEJ; Hauptman-Woodward Medical Research Institute, 700 Ellicott St, Buffalo, New York 14203, USA.
  • Chen CH; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27514, USA.
  • de la Cruz MJ; Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA.
  • Decato DA; Chemistry and Biochemistry, University of Montana, 32 Campus Drive, Missoula, Montana 59812, USA.
  • Eng ET; Simons Electron Microscopy Center, New York Structural Biology Center, 89 Convent Ave, New York, New York 10027, USA.
  • Flatt KM; Materials Research Laboratory, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA.
  • Gulati S; Gatan Inc., Pleasanton, CA 94588, USA.
  • Li Y; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, USA.
  • Lomba CJ; Department of Physics, Quantitative Biology Institute, Yale University, 260 Whitney Ave., New Haven, Connecticut 06520-8103, USA.
  • Mercado B; Department of Chemistry, Yale University, New Haven, Connecticut 06520, USA.
  • Miller J; Simons Electron Microscopy Center, New York Structural Biology Center, 89 Convent Ave, New York, New York 10027, USA.
  • Palatinus L; Institute of Physics of the CAS/NanED, Na Slovance 1999/2, Prague 192000, Czech Republic.
  • Rice WJ; Department of Cell Biology, NYU Grossman School of Medicine, 540 First Ave, New York, New York 10016, USA.
  • Waterman D; Research Complex at Harwell, UKRI-STFC Rutherford Appleton Laboratory, Harwell, Didcot, Oxfordshire, OX11 0FA, England, United Kingdom.
  • Zimanyi CM; Simons Electron Microscopy Center, New York Structural Biology Center, 89 Convent Ave, New York, New York 10027, USA.
Acta Crystallogr C Struct Chem ; 80(Pt 6): 179-189, 2024 06 01.
Article em En | MEDLINE | ID: mdl-38712546
ABSTRACT
We report on the latest advancements in Microcrystal Electron Diffraction (3D ED/MicroED), as discussed during a symposium at the National Center for CryoEM Access and Training housed at the New York Structural Biology Center. This snapshot describes cutting-edge developments in various facets of the field and identifies potential avenues for continued progress. Key sections discuss instrumentation access, research applications for small molecules and biomacromolecules, data collection hardware and software, data reduction software, and finally reporting and validation. 3D ED/MicroED is still early in its wide adoption by the structural science community with ample opportunities for expansion, growth, and innovation.
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Software / Microscopia Crioeletrônica Idioma: En Revista: Acta Crystallogr C Struct Chem Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Software / Microscopia Crioeletrônica Idioma: En Revista: Acta Crystallogr C Struct Chem Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos