Multi-locus sequence typing of Escherichia coli isolated from clinical samples in Jordan.
J Infect Dev Ctries
; 18(4): 571-578, 2024 Apr 30.
Article
em En
| MEDLINE
| ID: mdl-38728632
ABSTRACT
INTRODUCTION:
Escherichia coli (E. coli) is the major cause of extraintestinal infections in the urinary tracts and bloodstream in humans in the community and health care institutions. Several studies on the genetic characterization of E. coli among clinical and environmental isolates were performed and revealed a wide diversity of sequence types (STs). In Jordan, phenotypic and genetic features of E. coli were extensively studied but there is still a need to identify the STs that inhabit the community.METHODOLOGY:
In this study, multi-locus sequence typing (MLST) was performed on archived clinical E. coli isolates collected from different hospitals in Jordan and the identified STs were extensively analyzed.RESULTS:
Genotyping of 92 E. coli isolates revealed 34 STs and 9 clonal complexes. The frequencies of STs ranged between 1 to 23 observations. The most frequent STs among E. coli isolates were ST131 (n = 23), ST69 (n = 19), ST998 (n = 7), ST2083 (n = 5), and ST540 (n = 4). These five ST accounted for up to 60% of the 92 E. coli isolates. Based on the MLST database, the STs reported in this work were world widely recognized in humans, animals, and in the environment.CONCLUSIONS:
This study has elaborated more knowledge about the genotypes of E. coli in Jordan, with recommendations for future studies to correlate its genotypes with virulence and resistance genes.Palavras-chave
Texto completo:
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Bases de dados:
MEDLINE
Assunto principal:
Escherichia coli
/
Infecções por Escherichia coli
/
Tipagem de Sequências Multilocus
/
Genótipo
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Infect Dev Ctries
Assunto da revista:
DOENCAS TRANSMISSIVEIS
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Jordânia