The Management of Mild Pulmonary Hypertension in Clinical Practice.
Ann Am Thorac Soc
; 21(8): 1115-1123, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-38747696
ABSTRACT
The definition of pulmonary hypertension (PH) has been revised recently, with the mean pulmonary artery pressure (mPAP) threshold (assessed by right heart catheterization) reduced from ⩾25 mm Hg to >20 mm Hg. This change reflects the mPAP upper limit of normal and a lower limit that is independently associated with adverse outcomes. To improve the specificity of diagnosing pathogenic increases in mPAP, however, a diagnosis of precapillary PH now also includes pulmonary vascular resistance >2.0 Wood units (WU) (lowered from >3.0 WU). These changes are positioned to capture approximately 55% more patients with PH. Because all clinical trials showing a benefit of pulmonary vasodilator therapy in precapillary PH used the classical hemodynamic definition, the approach to the diagnosis and management of patients with mild PH (i.e., mPAP 21-24 mm Hg and pulmonary vascular resistance 2-3 WU) requires particular consideration. Here, we use a question/answer format to discuss key areas in the management of mild PH, including practical information tailored to clinicians without training in PH.
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Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Resistência Vascular
/
Vasodilatadores
/
Cateterismo Cardíaco
/
Hipertensão Pulmonar
Limite:
Humans
Idioma:
En
Revista:
Ann Am Thorac Soc
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Áustria