Synthetic Genomics: Repurposing Biological Systems for Applications in Engineering Biology.
ACS Synth Biol
; 13(5): 1394-1399, 2024 05 17.
Article
em En
| MEDLINE
| ID: mdl-38757697
ABSTRACT
Substantial improvements in DNA sequencing and synthesis technologies and increased understanding of genome biology have empowered the development of synthetic genomics. The ability to design and construct engineered living cells boosted up by synthetic chromosomes provides opportunities to tackle enormous current and future challenges faced by humanity and the planet. Here we review the progresses, considerations, challenges, and future direction of the "design-build-test-learn" cycle used in synthetic genomics. We also discuss future applications enabled by synthetic genomics as this emerging field shapes and revolutionizes biomanufacturing and biomedicine.
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Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Genômica
/
Biologia Sintética
Limite:
Humans
Idioma:
En
Revista:
ACS Synth Biol
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China