Prediction of Acute Kidney Injury After Coronary Artery Bypass Graft From Preoperative Serum Uric Acid.
J Cardiothorac Vasc Anesth
; 38(10): 2247-2253, 2024 Oct.
Article
em En
| MEDLINE
| ID: mdl-38890081
ABSTRACT
OBJECTIVE:
To examine the association of an elevated level of uric acid (UA) in the bloodstream with an increased likelihood of acute kidney injury (AKI) following coronary artery bypass grafting (CABG) surgery.DESIGN:
Retrospective cohort study using a multivariate logistic regression model.SETTING:
Single institution.PARTICIPANTS:
Recipients of CABG surgery. INTERVENTION None. MEASUREMENTS AND MAINRESULTS:
A total of 761 individuals who underwent CABG were included in the study. The participants were categorized into 4 groups based on their UA level Q1 group (UA <292.5 µmol/L), Q2 group (292.5 ≤ UA <353 µmol/L), Q3 group (353 ≤ UA < 423 µmol/L), and Q4 group (UA ≥423 µmol/L). A total of 167 patients, accounting for 21.9% of the sample, experienced postoperative AKI. The study found a significantly higher risk of AKI in the Q4 group compared to the Q1 group (40.4% v 8.9%; p < 0.001). After adjustment for confounding variables, an independent association between serum UA concentration and an elevated risk of AKI post-CABG was identified (odds ratio, 6.41; 95% confidence interval, 3.49-12.32; p < 0.001; p for trend < 0.001).CONCLUSIONS:
There is a relationship between preoperative blood UA level and the occurrence of AKI following CABG surgery.Palavras-chave
Texto completo:
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Bases de dados:
MEDLINE
Assunto principal:
Complicações Pós-Operatórias
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Ácido Úrico
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Biomarcadores
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Ponte de Artéria Coronária
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Injúria Renal Aguda
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Cardiothorac Vasc Anesth
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J. cardiothoracic vasc. anest
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Journal of cardiothoracic and vascular anesthesia
Assunto da revista:
ANESTESIOLOGIA
/
CARDIOLOGIA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China