One Molecule, Many Faces: Repositioning Cardiovascular Agents for Advanced Wound Healing.
Molecules
; 29(12)2024 Jun 20.
Article
em En
| MEDLINE
| ID: mdl-38931002
ABSTRACT
Chronic wound treatments pose a challenge for healthcare worldwide, particularly for the people in developed countries. Chronic wounds significantly impair quality of life, especially among the elderly. Current research is devoted to novel approaches to wound care by repositioning cardiovascular agents for topical wound treatment. The emerging field of medicinal products' repurposing, which involves redirecting existing pharmaceuticals to new therapeutic uses, is a promising strategy. Recent studies suggest that medicinal products such as sartans, beta-blockers, and statins have unexplored potential, exhibiting multifaceted pharmacological properties that extend beyond their primary indications. The purpose of this review is to analyze the current state of knowledge on the repositioning of cardiovascular agents' use and their molecular mechanisms in the context of wound healing.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Cicatrização
/
Fármacos Cardiovasculares
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Reposicionamento de Medicamentos
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Molecules
Assunto da revista:
BIOLOGIA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Polônia