The Potential Mechanism of Remission in Type 2 Diabetes Mellitus After Vertical Sleeve Gastrectomy.
Obes Surg
; 34(8): 3071-3083, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-38951388
ABSTRACT
In recent years, there has been a gradual increase in the prevalence of obesity and type 2 diabetes mellitus (T2DM), with bariatric surgery remaining the most effective treatment strategy for these conditions. Vertical sleeve gastrectomy (VSG) has emerged as the most popular surgical procedure for bariatric/metabolic surgeries, effectively promoting weight loss and improving or curing T2DM. The alterations in the gastrointestinal tract following VSG may improve insulin secretion and resistance by increasing incretin secretion (especially GLP-1), modifying the gut microbiota composition, and through mechanisms dependent on weight loss. This review focuses on the potential mechanisms through which the enhanced action of incretin and metabolic changes in the digestive system after VSG may contribute to the remission of T2DM.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Obesidade Mórbida
/
Redução de Peso
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Diabetes Mellitus Tipo 2
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Gastrectomia
Limite:
Humans
Idioma:
En
Revista:
Obes Surg
/
Obes. surg
/
Obesity surgery
Assunto da revista:
METABOLISMO
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China