Altering cold-regulated gene expression decouples the salicylic acid-growth trade-off in Arabidopsis.
Plant Cell
; 36(10): 4293-4308, 2024 Oct 03.
Article
em En
| MEDLINE
| ID: mdl-39056470
ABSTRACT
In Arabidopsis (Arabidopsis thaliana), overproduction of salicylic acid (SA) increases disease resistance and abiotic stress tolerance but penalizes growth. This growth-defense trade-off has hindered the adoption of SA-based disease management strategies in agriculture. However, investigation of how SA inhibits plant growth has been challenging because many SA-hyperaccumulating Arabidopsis mutants have developmental defects due to the pleiotropic effects of the underlying genes. Here, we heterologously expressed a bacterial SA synthase gene in Arabidopsis and observed that elevated SA levels decreased plant growth and reduced the expression of cold-regulated (COR) genes in a dose-dependent manner. Growth suppression was exacerbated at below-ambient temperatures. Severing the SA-responsiveness of individual COR genes was sufficient to overcome the growth inhibition caused by elevated SA at ambient and below-ambient temperatures while preserving disease- and abiotic-stress-related benefits. Our results show the potential of decoupling SA-mediated growth and defense trade-offs for improving crop productivity.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Arabidopsis
/
Temperatura Baixa
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Regulação da Expressão Gênica de Plantas
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Ácido Salicílico
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Proteínas de Arabidopsis
Idioma:
En
Revista:
Plant Cell
Assunto da revista:
BOTANICA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos