Engineering an upconversion fluorescence sensing platform with "off-on" pattern through specific DNAzyme-mediated signal amplification for supersensitive detection of uranyl ion.

Zhang, Xinyu; Wang, Yue; Gong, Mi; Xiong, Lihao; Song, Jiayi; Chen, Sihan; Tong, Yuqi; Liu, Yu; Li, Le; Zhen, Deshuai

Zhang, Xinyu; Wang, Yue; Gong, Mi; Xiong, Lihao; Song, Jiayi; Chen, Sihan; Tong, Yuqi; Liu, Yu; Li, Le; Zhen, Deshuai.

Afiliação

Zhang X; Hunan Key Laboratory of Typical Environment Pollution and Health Hazards, College of Public Health, Hengyang Medical School, University of South China, Hengyang, 421001, P. R. China.
Wang Y; Hunan Key Laboratory of Typical Environment Pollution and Health Hazards, College of Public Health, Hengyang Medical School, University of South China, Hengyang, 421001, P. R. China.
Gong M; Hunan Key Laboratory of Typical Environment Pollution and Health Hazards, College of Public Health, Hengyang Medical School, University of South China, Hengyang, 421001, P. R. China.
Xiong L; Hunan Key Laboratory of Typical Environment Pollution and Health Hazards, College of Public Health, Hengyang Medical School, University of South China, Hengyang, 421001, P. R. China.
Song J; Hunan Key Laboratory of Typical Environment Pollution and Health Hazards, College of Public Health, Hengyang Medical School, University of South China, Hengyang, 421001, P. R. China.
Chen S; Hunan Key Laboratory of Typical Environment Pollution and Health Hazards, College of Public Health, Hengyang Medical School, University of South China, Hengyang, 421001, P. R. China. 172140411@qq.com.
Tong Y; Hunan Key Laboratory of Typical Environment Pollution and Health Hazards, College of Public Health, Hengyang Medical School, University of South China, Hengyang, 421001, P. R. China.
Liu Y; State Key Laboratory of Chemo/Biosensing and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China.
Li L; Hunan Key Laboratory of Typical Environment Pollution and Health Hazards, College of Public Health, Hengyang Medical School, University of South China, Hengyang, 421001, P. R. China. usclile@126.com.
Zhen D; Hunan Key Laboratory of Typical Environment Pollution and Health Hazards, College of Public Health, Hengyang Medical School, University of South China, Hengyang, 421001, P. R. China. zhends.1987@163.com.

Mikrochim Acta ; 191(8): 503, 2024 Aug 03.

Article em En | MEDLINE | ID: mdl-39096341

ABSTRACT

ABSTRACT

An upconversion fluorescence sensing platform was developed with upconversion nanoparticles (UCNPs) as energy donors and gold nanoparticles (AuNPs) as energy acceptors, based on the FRET principle. They were used for quantitative detection of uranyl ions (UO22+) by amplifying the signal of the hybrid chain reaction (HCR). When UO22+ are introduced, the FRET between AuNPs and UCNPs can be modulated through a HCR in the presence of high concentrations of sodium chloride. This platform provides exceptional sensitivity, with a detection limit as low as 68 pM for UO22+ recognition. We have successfully validated the reliability of this method by analyzing authentic water samples, achieving satisfactory recoveries (89.00%-112.50%) that are comparable to those of ICP-MS. These results indicate that the developed sensing platform has the capability to identify trace UO22+ in complex environmental samples.

Palavras-chave

Deoxyribozyme; Fluorescence resonance energy transfer; Hybrid chain reaction; Upconversion nanoparticles; Uranyl

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Mikrochim Acta Ano de publicação: 2024 Tipo de documento: Article