A Rare Case of Ruptured Distal Posterior Cerebral Artery Aneurysm Followed by Middle Cerebral Artery Occlusion due to Delayed Diagnosis of Infective Endocarditis.

ABSTRACT

A 31-year-old female presented to our hospital with sudden headache and altered consciousness. Computed tomography showed left acute subdural hematoma, and digital subtraction angiography revealed a small aneurysm on the left distal posterior cerebral artery. Coil embolization was conducted, and the patient was discharged with no neurological deficits. However, two weeks later, she presented with complete left hemiplegia and with the National Institutes of Health Stroke Scale of 20. Magnetic resonance angiography showed the occlusion of right middle cerebral artery, and the Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Score was four. Mechanical thrombectomy was conducted. Complete recanalization was achieved, and the patient recovered favorably. Although she showed no symptoms of infection such as fever throughout the treatment of aneurysm and thrombectomy, her blood culture was positive for streptococcus mitis. Furthermore, the thrombus retrieved by thrombectomy showed bacterial mass, and transesophageal echocardiography (TEE) showed vegetation on the mitral valve that could not be detected by transthoracic echocardiography. Therefore, the patient was diagnosed with infective endocarditis (IE). She was administered penicillin for 6 weeks and was discharged with no neurological deficits. When treating young patients with small aneurysms in rare locations, IE should be suspected, and blood culture and TEE should be conducted, even when there are no obvious symptoms of systemic infection.