Anti-implantation activity of the fruit of Lagenaria breviflora Robert.
J Ethnopharmacol
; 13(3): 281-8, 1985 Jul.
Article
em En
| MEDLINE
| ID: mdl-4058031
ABSTRACT
The fruit of Lagenaria breviflora Robert (Adenopus breviflorus Benth) family Cucurbitaceae used by natives as an abortifacient in Nigeria, was investigated for anti-implantation activity. The ethyl acetate extract of the whole fruit and methanol extract of the seed were very toxic to rats. Using ten female virgin albino rats for each extract, the World Health Organization special protocol and doses on a moisture-free basis 20 g/kg whole fruit methanol extract gave 60% anti-implantation activity, 2.5 g/kg fruit pulp gave 80% and 5 g/kg fruit pulp gave 100% activity while 2 g/kg seed also gave 100% activity but four of the rats died. Statistical evaluation of the data showed that the results were significant.
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Bases de dados:
MEDLINE
Assunto principal:
Implantação do Embrião
/
Plantas Medicinais
/
Abortivos
/
Abortivos não Esteroides
Limite:
Animals
/
Pregnancy
País/Região como assunto:
Africa
Idioma:
En
Revista:
J Ethnopharmacol
Ano de publicação:
1985
Tipo de documento:
Article