An analysis of water movement between myocardial tissue and capillary blood during reactive hyperemia.
Jpn J Physiol
; 29(1): 1-13, 1979.
Article
em En
| MEDLINE
| ID: mdl-449120
ABSTRACT
The colloid osmotic pressure (COP) of blood from the great cardiac vein was continuously measured by means of a membrane colloid osmometer during the reactive hyperemia following temporary occlusion of the anterior descending branch of the left coronary artery in anesthetized open-chest dogs. The COP increased sharply after releasing the occlusion, then decreased below the preocclusion level before gradually returning to it. These findings indicate that a measurable amount of water moved from the capillary blood into the myocardial tissues and then flowed back slowly into the capillary blood. To analyse the factors affecting this water movement, a method is proposed in which the Starling mechanism is combined with the interstitial volume elasticity and a steady-state solution of a Navier-Stokes equation. The pressure observed with a catheter wedged into a branch of the great cardiac vein was used as a measure of capillary perfusion pressure. During the coronary arterial occlusion, the filtration constant increased while the volume elasticity of the myocardial interstitial spaces decreased rapidly. The filtration constant and volume elasticity of the interstitial space under normal conditions were approximately estimated to be 2.4 X 10(-11) cm/(sec.dyn.cm-2) and 1.1 X 10(7) dyn.cm-2, respectively.
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Bases de dados:
MEDLINE
Assunto principal:
Permeabilidade Capilar
/
Água
/
Vasos Coronários
/
Hiperemia
/
Miocárdio
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Jpn J Physiol
Ano de publicação:
1979
Tipo de documento:
Article