Dopamine-beta-hydroxylase: evidence for increased activity in sympathetic neurons during psychotic states.
Science
; 182(4115): 923-4, 1973 Nov 20.
Article
em En
| MEDLINE
| ID: mdl-4745595
ABSTRACT
Tritiated dopamine was infused into psychiatric patients during acute psychotic episodes and in remission. An index of the activity of dopamine-beta-hydroxylase of salivary gland sympathetic neurons was determined by measuring the distribution of tritiated metabolites in salivary fluid. Increased synthesis of norepinephrine occurred in acute schizophrenia and in the manic state of manic-depressive psychosis but not in the depressed phase.
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Bases de dados:
MEDLINE
Assunto principal:
Glândulas Salivares
/
Esquizofrenia
/
Sistema Nervoso Simpático
/
Transtorno Bipolar
/
Dopamina beta-Hidroxilase
Limite:
Humans
/
Male
Idioma:
En
Revista:
Science
Ano de publicação:
1973
Tipo de documento:
Article