Clonal t(8;14)(p11;q31) in a case of reactive lymphoproliferation.
Genes Chromosomes Cancer
; 7(3): 165-8, 1993 Jul.
Article
em En
| MEDLINE
| ID: mdl-7687870
ABSTRACT
A clone with an unbalanced translocation t(8;14)(p11;q31), resulting in deletion of the distal part of the long arm of chromosome 14, 14q31 --> 14qter, was detected in a case of Piringer's lymphadenitis. Histopathologically no atypical cells or other signs of malignant lymphoma were found. Southern blot analyses showed no rearrangement of the immunoglobulin heavy chain gene (IGH) or the T-cell receptor gamma chain (TCRG) gene. The case exemplifies that the detection of a chromosomally aberrant clone does not necessarily prove that a lymphoproliferative process is malignant.
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Bases de dados:
MEDLINE
Assunto principal:
Aberrações Cromossômicas
/
Linfadenite
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Genes Chromosomes Cancer
Assunto da revista:
BIOLOGIA MOLECULAR
/
NEOPLASIAS
Ano de publicação:
1993
Tipo de documento:
Article
País de afiliação:
Alemanha