Motor neurone disease--a study of prevalence and disability.
QJM
; 87(11): 693-9, 1994 Nov.
Article
em En
| MEDLINE
| ID: mdl-7820544
ABSTRACT
We conducted a point prevalence study of motor neurone disease in the counties of South Glamorgan, Mid Glamorgan and Gwent, whose combined population is estimated at 1,394,400. A total of 56 patients were identified, giving a point prevalence for motor neurone disease in this area of 4.02/100,000 on 22/06/92. These cases were reclassified according to the World Federation of Neurology criteria for amyotrophic lateral sclerosis following a further clinical assessment, when disability was also evaluated (in 49 cases). Seven patients were reclassified on review of their medical records alone. Overall, 38 were classified as either definite or probable cases, which gave a point prevalence of 2.73/100,000. Of these patients, 94% (46/49) were living at home, 43% (21/49) scored 15 or less on the Barthel index, 65% (32/49) had some degree of mobility impairment, and 20% (10/49) were wheelchair-dependent. Swallowing speed was reduced (< 10 ml/s) in 67% (33/49), with three requiring feeding through a percutaneous gastrostomy tube. Vital capacity was < 70% of predicted value for age, sex and height in 67% (29/43). One patient was receiving domiciliary ventilation. These results give a quantitative indication of the dependency in a population of patients with motor neurone disease.
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Bases de dados:
MEDLINE
Assunto principal:
Doença dos Neurônios Motores
Tipo de estudo:
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Humans
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
QJM
Assunto da revista:
MEDICINA
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Reino Unido