Mitogenic activity of new lectins from seeds of wild Artocarpus species from Vietnam.
C R Acad Sci III
; 319(5): 405-9, 1996 May.
Article
em En
| MEDLINE
| ID: mdl-8763740
ABSTRACT
Proliferative response of human peripheral blood mononuclear cells (PBMC) stimulated by new lectins purified from seeds of differents Artocarpus species from Vietnam (A. asperulus, A. heterophyllus, A. masticata, A. melinoxylus, A. parva and A. petelotii) was studied and compared to those of the lectin jacalin purified from jackfruit (A. heterophyllus) seeds collected in the island La Réunion. All lectins stimulated human PBMC to proliferate, with a variable efficiency of the mitogenic activity. Phenotypic analysis of cells recovered after 7 day-cultures showed that these lectins mostly stimulated CD4+ T lymphocytes. These results suggest that these lectins from different Artocarpus species are similar in terms of their mitogenic activity although their structural features are not identical.
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Bases de dados:
MEDLINE
Assunto principal:
Frutas
/
Lectinas
/
Mitógenos
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
C R Acad Sci III
Assunto da revista:
BIOLOGIA
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
França