Mice as models of human developmental disorders: natural and artificial mutants.
Curr Opin Genet Dev
; 6(3): 289-94, 1996 Jun.
Article
em En
| MEDLINE
| ID: mdl-8791521
ABSTRACT
Over the past year, the mouse has been used as a model to make significant contributions towards our understanding of human developmental disorders. The existence of both natural and artificial mouse mutants has not only facilitated the identification of mutations and provided candidate genes for human disorders but has also increased our knowledge regarding the cellular and molecular processes involved in normal mammalian embryogenesis.
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Bases de dados:
MEDLINE
Assunto principal:
Doenças Ósseas
/
Fissura Palatina
/
Surdez
/
Modelos Animais de Doenças
/
Defeitos do Tubo Neural
/
Obesidade
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Opin Genet Dev
Assunto da revista:
GENETICA
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
Reino Unido