Noninvasive assessment of stiffness and failure load of human vertebrae from CT-data.
Biomed Tech (Berl)
; 43(4): 82-8, 1998 Apr.
Article
em En
| MEDLINE
| ID: mdl-9611393
ABSTRACT
A calculational method based on noninvasively derived data for the assessment of the mechanical quality of individual vertebrae is presented. Dimensional data obtained from serial, segmented CT scans were used as the geometric input for a newly developed finite element model designed to calculate stiffness and failure load of these complex bone structures. Mechanical, structural data for cancellous bone was obtained by measurements of the compressive strength and failure load of actual vertebral specimens obtained at autopsy. The stiffness and failure load calculated by the newly developed finite element model were compared with the data obtained from mechanical measurements of vertebral specimens. A high correlation between measured and calculated failure load was found (r = 0.89, p < 0.001, n = 16). The correlation between the failure load and bone mineral density (BMD) was significant (r = 0.82, p < 0.001, n = 16). A similar correlation between calculated and measured stiffness (r = 0.81, p < 0.001, n = 15) was also found using the finite element model described herein. Thus the newly developed calculation methodology has been verified and can be used to predict the failure load and stiffness of osteoporotic vertebrae using data obtained non-invasively from CT scans.
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Bases de dados:
MEDLINE
Assunto principal:
Vértebras Torácicas
/
Processamento de Imagem Assistida por Computador
/
Tomografia Computadorizada por Raios X
/
Densidade Óssea
/
Suporte de Carga
/
Vértebras Lombares
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Biomed Tech (Berl)
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Alemanha