Detalhe da pesquisa
1.
KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer.
Cell
; 168(5): 817-829.e15, 2017 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28215705
2.
Diverse tumorigenic consequences of human papillomavirus integration in primary oropharyngeal cancers.
Genome Res
; 32(1): 55-70, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34903527
3.
Human papillomavirus and the landscape of secondary genetic alterations in oral cancers.
Genome Res
; 29(1): 1-17, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30563911
4.
HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression.
PLoS Genet
; 14(1): e1007179, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29364907
5.
Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia.
Nature
; 513(7519): 512-6, 2014 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25043004
6.
In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.
Circ Res
; 121(8): 923-929, 2017 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28790199
7.
The bonobo genome compared with the chimpanzee and human genomes.
Nature
; 486(7404): 527-31, 2012 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22722832
8.
Clonal selection drives genetic divergence of metastatic medulloblastoma.
Nature
; 482(7386): 529-33, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22343890
9.
Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer.
Proc Natl Acad Sci U S A
; 112(19): 6128-33, 2015 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25918370
10.
Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability.
Genome Res
; 24(2): 185-99, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24201445
11.
An antisense promoter in mouse L1 retrotransposon open reading frame-1 initiates expression of diverse fusion transcripts and limits retrotransposition.
Nucleic Acids Res
; 42(7): 4546-62, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24493738
12.
Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance.
Genome Res
; 22(5): 870-84, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22367191
13.
Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras.
Nature
; 461(7262): 411-4, 2009 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-19727076
14.
How do mammalian transposons induce genetic variation? A conceptual framework: the age, structure, allele frequency, and genome context of transposable elements may define their wide-ranging biological impacts.
Bioessays
; 35(4): 397-407, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23319453
15.
A homozygous mutant embryonic stem cell bank applicable for phenotype-driven genetic screening.
Nat Methods
; 8(12): 1071-7, 2011 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22020066
16.
Transcriptomic, Proteomic, and Genomic Mutational Fraction Differences Based on HPV Status Observed in Patient-Derived Xenograft Models of Penile Squamous Cell Carcinoma.
Cancers (Basel)
; 16(5)2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38473423
17.
Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus.
Blood
; 117(6): 2022-32, 2011 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21163920
18.
Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents.
Proc Natl Acad Sci U S A
; 107(11): 5106-11, 2010 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20194733
19.
New genes involved in cancer identified by retroviral tagging.
Nat Genet
; 32(1): 166-74, 2002 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12185365
20.
Intratumoral Heterogeneity and Clonal Evolution Induced by HPV Integration.
Cancer Discov
; 13(4): 910-927, 2023 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36715691