Detalhe da pesquisa
1.
Folate and Cobalamin Deficiencies during Pregnancy Disrupt the Glucocorticoid Response in Hypothalamus through N-Homocysteinilation of the Glucocorticoid Receptor.
Int J Mol Sci
; 24(12)2023 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37372992
2.
Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR.
Nucleic Acids Res
; 46(15): 7844-7857, 2018 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30016500
3.
The Stimulation of Neurogenesis Improves the Cognitive Status of Aging Rats Subjected to Gestational and Perinatal Deficiency of B9-12 Vitamins.
Int J Mol Sci
; 21(21)2020 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33126444
4.
Brain Susceptibility to Methyl Donor Deficiency: From Fetal Programming to Aging Outcome in Rats.
Int J Mol Sci
; 20(22)2019 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31739389
5.
Methyl donor deficiency impairs bone development via peroxisome proliferator-activated receptor-γ coactivator-1α-dependent vitamin D receptor pathway.
FASEB J
; 30(10): 3598-3612, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27435264
6.
Methyl-deficient diet promotes colitis and SIRT1-mediated endoplasmic reticulum stress.
Gut
; 65(4): 595-606, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25608526
7.
Folate- and vitamin B12-deficient diet during gestation and lactation alters cerebellar synapsin expression via impaired influence of estrogen nuclear receptor α.
FASEB J
; 29(9): 3713-25, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26018677
8.
Interaction between methionine synthase isoforms and MMACHC: characterization in cblG-variant, cblG and cblC inherited causes of megaloblastic anaemia.
Hum Mol Genet
; 22(22): 4591-601, 2013 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23825108
9.
Early methyl donor deficiency alters cAMP signaling pathway and neurosteroidogenesis in the cerebellum of female rat pups.
Am J Physiol Endocrinol Metab
; 307(11): E1009-19, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25294213
10.
Gestational methyl donor deficiency alters key proteins involved in neurosteroidogenesis in the olfactory bulbs of newborn female rats and is associated with impaired olfactory performance.
Br J Nutr
; 111(6): 1021-31, 2014 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24229781
11.
Multiomic analysis in fibroblasts of patients with inborn errors of cobalamin metabolism reveals concordance with clinical and metabolic variability.
EBioMedicine
; 99: 104911, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38168585
12.
Homocysteinylation of neuronal proteins contributes to folate deficiency-associated alterations of differentiation, vesicular transport, and plasticity in hippocampal neuronal cells.
FASEB J
; 26(10): 3980-92, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22713523
13.
Cognitive Impairment Is Associated with AMPAR Glutamatergic Dysfunction in a Mouse Model of Neuronal Methionine Synthase Deficiency.
Cells
; 12(9)2023 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37174668
14.
A transgenic mice model of retinopathy of cblG-type inherited disorder of one-carbon metabolism highlights epigenome-wide alterations related to cone photoreceptor cells development and retinal metabolism.
Clin Epigenetics
; 15(1): 158, 2023 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37798757
15.
Methyl donor deficiency impairs fatty acid oxidation through PGC-1α hypomethylation and decreased ER-α, ERR-α, and HNF-4α in the rat liver.
J Hepatol
; 57(2): 344-51, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22521344
16.
Methyl donor deficiency induces cardiomyopathy through altered methylation/acetylation of PGC-1α by PRMT1 and SIRT1.
J Pathol
; 225(3): 324-35, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21633959
17.
Vitamin B12 deficiency reduces proliferation and promotes differentiation of neuroblastoma cells and up-regulates PP2A, proNGF, and TACE.
Proc Natl Acad Sci U S A
; 106(51): 21930-5, 2009 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19959661
18.
ALDH1L2 Knockout in U251 Glioblastoma Cells Reduces Tumor Sphere Formation by Increasing Oxidative Stress and Suppressing Methionine Dependency.
Nutrients
; 14(9)2022 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35565854
19.
Methyl deficient diet aggravates experimental colitis in rats.
J Cell Mol Med
; 15(11): 2486-97, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21199330
20.
Vitamin B12 Deficiency Dysregulates m6A mRNA Methylation of Genes Involved in Neurological Functions.
Mol Nutr Food Res
; 65(17): e2100206, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34291881