Detalhe da pesquisa
1.
Structural insights into CodY activation and DNA recognition.
Nucleic Acids Res
; 51(14): 7631-7648, 2023 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37326020
2.
Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics.
Proc Natl Acad Sci U S A
; 119(43): e2210912119, 2022 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36252016
3.
Synthesis of Three-Dimensional Ring Fused Heterocycles by a Selective [4 + 2] Cycloaddition Between Bicyclic Thiazolo 2-Pyridones and Arynes.
J Org Chem
; 89(1): 731-739, 2024 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38093677
4.
THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates.
Proc Natl Acad Sci U S A
; 118(47)2021 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34785593
5.
A 2-pyridone amide inhibitor of transcriptional activity in Chlamydia trachomatis.
Antimicrob Agents Chemother
; 95(5)2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33593835
6.
The bacterial curli system possesses a potent and selective inhibitor of amyloid formation.
Mol Cell
; 57(3): 445-55, 2015 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25620560
7.
Effects of individual differences, society, and culture on youth-rated problems and strengths in 38 societies.
J Child Psychol Psychiatry
; 63(11): 1297-1307, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35167140
8.
Selective auxin agonists induce specific AUX/IAA protein degradation to modulate plant development.
Proc Natl Acad Sci U S A
; 116(13): 6463-6472, 2019 03 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30850516
9.
Chemical disarming of isoniazid resistance in Mycobacterium tuberculosis.
Proc Natl Acad Sci U S A
; 116(21): 10510-10517, 2019 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31061116
10.
Tandem Ring Opening/Intramolecular [2 + 2] Cycloaddition Reaction for the Synthesis of Cyclobutane Fused Thiazolino-2-Pyridones.
J Org Chem
; 86(23): 16582-16592, 2021 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34767366
11.
Selected applications of Meldrum's acid - a tutorial.
Org Biomol Chem
; 19(23): 5014-5027, 2021 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34019615
12.
K2S2O8-mediated coupling of 6-amino-7-aminomethyl-thiazolino-pyridones with aldehydes to construct amyloid affecting pyrimidine-fused thiazolino-2-pyridones.
Org Biomol Chem
; 19(44): 9758-9772, 2021 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34730163
13.
Intramolecular Povarov Reactions for the Synthesis of Chromenopyridine Fused 2-Pyridone Polyheterocycles Binding to α-Synuclein and Amyloid-ß Fibrils.
J Org Chem
; 85(21): 14174-14189, 2020 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33099999
14.
Inhibition of curli assembly and Escherichia coli biofilm formation by the human systemic amyloid precursor transthyretin.
Proc Natl Acad Sci U S A
; 114(46): 12184-12189, 2017 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29087319
15.
A role for the auxin precursor anthranilic acid in root gravitropism via regulation of PIN-FORMED protein polarity and relocalisation in Arabidopsis.
New Phytol
; 223(3): 1420-1432, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31038751
16.
Viral mimetic priming enhances α-synuclein-induced degeneration: Implications for Parkinson's disease.
Brain Behav Immun
; 80: 525-535, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31029796
17.
Pyridine-Fused 2-Pyridones via Povarov and A3 Reactions: Rapid Generation of Highly Functionalized Tricyclic Heterocycles Capable of Amyloid Fibril Binding.
J Org Chem
; 84(7): 3887-3903, 2019 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30862161
18.
Testing Syndromes of Psychopathology in Parent and Youth Ratings Across Societies.
J Clin Child Adolesc Psychol
; 48(4): 596-609, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-29364720
19.
Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria.
Proc Natl Acad Sci U S A
; 113(51): 14733-14738, 2016 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27930316
20.
Visible-Light-Mediated Synthesis of ß-Chloro Ketones from Aryl Cyclopropanes.
Angew Chem Int Ed Engl
; 58(25): 8577-8580, 2019 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30901148