Detalhe da pesquisa
1.
Small-molecule IKKß activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth.
Proc Natl Acad Sci U S A
; 119(18): e2115071119, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35476515
2.
Crosstalk of hepatocyte nuclear factor 4a and glucocorticoid receptor in the regulation of lipid metabolism in mice fed a high-fat-high-sugar diet.
Lipids Health Dis
; 21(1): 46, 2022 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35614477
3.
Intramuscular and subcutaneous administration of antiretroviral drugs, compared with oral, enhances delivery to lymphoid tissues in BALB/c mice.
J Antimicrob Chemother
; 76(10): 2651-2658, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34312680
4.
A year-long extended release nanoformulated cabotegravir prodrug.
Nat Mater
; 19(8): 910-920, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32341511
5.
Preliminary preclinical study of Chol-DsiRNA polyplexes formed with PLL[30]-PEG[5K] for the RNAi-based therapy of breast cancer.
Nanomedicine
; 33: 102363, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33545405
6.
Synthesis and Characterization of Long-Acting Darunavir Prodrugs.
Mol Pharm
; 17(1): 155-166, 2020 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31742407
7.
Head-to-head comparative pharmacokinetic and biodistribution (PK/BD) study of two dexamethasone prodrug nanomedicines on lupus-prone NZB/WF1 mice.
Nanomedicine
; 29: 102266, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32679269
8.
Assessing the lymphoid tissue bioavailability of antiretrovirals in human primary lymphoid endothelial cells and in mice.
J Antimicrob Chemother
; 74(10): 2974-2978, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31335938
9.
Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice.
Hepatology
; 67(6): 2150-2166, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29159825
10.
Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators.
Bioorg Med Chem Lett
; 29(6): 791-796, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718161
11.
Pharmacokinetics of a Long-Acting Nanoformulated Dolutegravir Prodrug in Rhesus Macaques.
Antimicrob Agents Chemother
; 62(1)2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29061742
12.
Increased glycine-amidated hyocholic acid correlates to improved early weight loss after sleeve gastrectomy.
Surg Endosc
; 32(2): 805-812, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28779240
13.
Species differences in bile acids I. Plasma and urine bile acid composition.
J Appl Toxicol
; 38(10): 1323-1335, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29785833
14.
Species differences in bile acids II. Bile acid metabolism.
J Appl Toxicol
; 38(10): 1336-1352, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29845631
15.
Simultaneous LC-MS/MS analysis of eicosanoids and related metabolites in human serum, sputum and BALF.
Biomed Chromatogr
; 32(3)2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28975688
16.
Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma.
J Lipid Res
; 58(12): 2275-2288, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28986437
17.
Leveraging of Rifampicin-Dosed Cynomolgus Monkeys to Identify Bile Acid 3-O-Sulfate Conjugates as Potential Novel Biomarkers for Organic Anion-Transporting Polypeptides.
Drug Metab Dispos
; 45(7): 721-733, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28396527
18.
Pharmacokinetic and Biodistribution Studies of HPMA Copolymer Conjugates in an Aseptic Implant Loosening Mouse Model.
Mol Pharm
; 14(5): 1418-1428, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28343392
19.
Impaired synaptic development in a maternal immune activation mouse model of neurodevelopmental disorders.
Brain Behav Immun
; 50: 249-258, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26218293
20.
Irreversible binding of an anticancer compound (BI-94) to plasma proteins.
Xenobiotica
; 45(10): 858-73, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25869245