Detalhe da pesquisa
1.
Targeting MCL-1 and BCL-2 with polatuzumab vedotin and venetoclax overcomes treatment resistance in R/R non-Hodgkin lymphoma: Results from preclinical models and a Phase Ib study.
Am J Hematol
; 98(3): 449-463, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36594167
2.
Effective treatment of HER2-amplified breast cancer by targeting HER3 and ß1 integrin.
Breast Cancer Res Treat
; 155(3): 431-40, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26860947
3.
HER3 signalling is regulated through a multitude of redundant mechanisms in HER2-driven tumour cells.
Biochem J
; 447(3): 417-25, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22853430
4.
The role of HER3, the unpretentious member of the HER family, in cancer biology and cancer therapeutics.
Semin Cell Dev Biol
; 21(9): 944-50, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20816829
5.
Targeting EGFR activity in blood vessels is sufficient to inhibit tumor growth and is accompanied by an increase in VEGFR-2 dependence in tumor endothelial cells.
Microvasc Res
; 76(1): 15-22, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18440031
6.
Tumor endothelial cells express epidermal growth factor receptor (EGFR) but not ErbB3 and are responsive to EGF and to EGFR kinase inhibitors.
Cancer Res
; 66(4): 2173-80, 2006 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16489018
7.
Tumor-associated endothelial cells with cytogenetic abnormalities.
Cancer Res
; 64(22): 8249-55, 2004 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15548691
8.
Gene expression profiling of ErbB receptor and ligand-dependent transcription.
Oncogene
; 23(7): 1428-38, 2004 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-14973552
9.
A TORC2-Akt Feed-Forward Topology Underlies HER3 Resiliency in HER2-Amplified Cancers.
Mol Cancer Ther
; 14(12): 2805-17, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26438156
10.
Chemical probing of HER2-amplified cancer cells identifies TORC2 as a particularly effective secondary target for combination with lapatinib.
Oncotarget
; 6(38): 41123-33, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26516700
11.
Disentangling multidimensional spatio-temporal data into their common and aberrant responses.
PLoS One
; 10(4): e0121607, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25901353
12.
Id2 promotes tumor cell migration and invasion through transcriptional repression of semaphorin 3F.
Cancer Res
; 70(9): 3823-32, 2010 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20388805
13.
Resiliency and vulnerability in the HER2-HER3 tumorigenic driver.
Sci Transl Med
; 2(16): 16ra7, 2010 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20371474
14.
Neuregulin-regulated gene expression in mammary carcinoma cells.
Exp Cell Res
; 309(1): 12-23, 2005 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-15963498