Detalhe da pesquisa
1.
Solid-State NMR Characterization of Lyophilized Formulations of Monoclonal Antibody Therapeutics.
Mol Pharm
; 20(3): 1480-1489, 2023 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36702622
2.
Principal component analysis for automated classification of 2D spectra and interferograms of protein therapeutics: influence of noise, reconstruction details, and data preparation.
J Biomol NMR
; 74(10-11): 643-656, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32700053
3.
Comparative Analysis of One-Dimensional Protein Fingerprint by Line Shape Enhancement and Two-Dimensional 1H,13C Methyl NMR Methods for Characterization of the Higher Order Structure of IgG1 Monoclonal Antibodies.
Anal Chem
; 92(9): 6366-6373, 2020 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32267681
4.
Best Practices in Utilization of 2D-NMR Spectral Data as the Input for Chemometric Analysis in Biopharmaceutical Applications.
J Chem Inf Model
; 60(4): 2339-2355, 2020 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32249579
5.
Chemometric Outlier Classification of 2D-NMR Spectra to Enable Higher Order Structure Characterization of Protein Therapeutics.
Chemometr Intell Lab Syst
; 1992020.
Artigo
em Inglês
| MEDLINE | ID: mdl-34135539
6.
Selective suppression of excipient signals in 2D 1H-13C methyl spectra of biopharmaceutical products.
J Biomol NMR
; 72(3-4): 149-161, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30483914
7.
Multivariate Analysis of Two-Dimensional 1H, 13C Methyl NMR Spectra of Monoclonal Antibody Therapeutics To Facilitate Assessment of Higher Order Structure.
Anal Chem
; 89(21): 11839-11845, 2017 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28937210
8.
2D (1)H(N), (15)N Correlated NMR Methods at Natural Abundance for Obtaining Structural Maps and Statistical Comparability of Monoclonal Antibodies.
Pharm Res
; 33(2): 462-75, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26453189
9.
Mapping monoclonal antibody structure by 2D 13C NMR at natural abundance.
Anal Chem
; 87(7): 3556-61, 2015 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25728213
10.
Interlaboratory Studies Using the NISTmAb to Advance Biopharmaceutical Structural Analytics.
Front Mol Biosci
; 9: 876780, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35601836
11.
Principal Component Analysis of 1D 1H Diffusion Edited NMR Spectra of Protein Therapeutics.
J Pharm Sci
; 110(10): 3385-3394, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34166704
12.
HNCO-based measurement of one-bond amide 15N-1H couplings with optimized precision.
J Biomol NMR
; 46(2): 175-89, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20012159
13.
Assessment of the Higher-Order Structure of Formulated Monoclonal Antibody Therapeutics by 2D Methyl Correlated NMR and Principal Component Analysis.
Curr Protoc Protein Sci
; 100(1): e105, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32407007
14.
Selective spin inversion in solution by magic field cross polarization.
J Magn Reson
; 308: 106588, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31561023
15.
Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics.
MAbs
; 11(1): 94-105, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30570405
16.
Heterologous recombinant expression of non-originator NISTmAb.
MAbs
; 10(6): 922-933, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29958062
17.
Application of Natural Isotopic Abundance ¹H-¹³C- and ¹H-¹5N-Correlated Two-Dimensional NMR for Evaluation of the Structure of Protein Therapeutics.
Methods Enzymol
; 566: 3-34, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26791974
18.
Unraveling long range residual dipolar coupling networks in strongly aligned proteins.
J Magn Reson
; 235: 26-31, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23917309
19.
Non-Uniform Sampling for All: More NMR Spectral Quality, Less Measurement Time.
Am Pharm Rev
; 20(4)2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29606851