Detalhe da pesquisa
1.
In vivo methods for imaging blood-brain barrier function and dysfunction.
Eur J Nucl Med Mol Imaging
; 50(4): 1051-1083, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36437425
2.
P-glycoprotein overactivity in epileptogenic developmental lesions measured in vivo using (R)-[11 C]verapamil PET.
Epilepsia
; 61(7): 1472-1480, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32627849
3.
Thrombin activation of protein C requires prior processing by a liver proprotein convertase.
J Biol Chem
; 292(25): 10564-10573, 2017 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28468828
4.
The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation: A NOVEL MECHANISM CAUSING FAMILIAL HYPERCHOLESTEROLEMIA.
J Biol Chem
; 292(5): 1573-1590, 2017 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27998977
5.
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor Degradation.
J Biol Chem
; 291(32): 16659-71, 2016 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27284008
6.
Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other.
J Biol Chem
; 290(30): 18609-20, 2015 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26085104
7.
Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes.
J Biol Chem
; 288(37): 26410-8, 2013 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23918928
8.
Early reduction in tumour [18F]fluorothymidine (FLT) uptake in patients with non-small cell lung cancer (NSCLC) treated with radiotherapy alone.
Eur J Nucl Med Mol Imaging
; 41(4): 682-93, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24504503
9.
Tolerability of tariquidar - A third generation P-gp inhibitor as add-on medication to antiseizure medications in drug-resistant epilepsy.
Seizure
; 119: 44-51, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38776617
10.
Thrombin activation of protein C requires prior processing by a liver proprotein convertase.
J Biol Chem
; 292(33): 13565, 2017 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28821605
11.
Proprotein convertase PC7 enhances the activation of the EGF receptor pathway through processing of the EGF precursor.
J Biol Chem
; 286(11): 9185-95, 2011 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21209099
12.
Proprotein convertase subtilisin/Kexin type 9 (PCSK9) single domain antibodies are potent inhibitors of low density lipoprotein receptor degradation.
J Biol Chem
; 291(51): 26586, 2016 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27986868
13.
Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10.
J Biol Chem
; 286(26): 22785-94, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21550985
14.
Erratum: Evaluation of 18F-IAM6067 as a sigma-1 receptor PET tracer for neurodegeneration in vivo in rodents and in human tissue: Erratum.
Theranostics
; 12(12): 5335-5336, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35910804
15.
Effects of the prosegment and pH on the activity of PCSK9: evidence for additional processing events.
J Biol Chem
; 285(52): 40965-78, 2010 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20937814
16.
Dissection of the endogenous cellular pathways of PCSK9-induced low density lipoprotein receptor degradation: evidence for an intracellular route.
J Biol Chem
; 284(42): 28856-64, 2009 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19635789
17.
PCSK9 impedes hepatitis C virus infection in vitro and modulates liver CD81 expression.
Hepatology
; 50(1): 17-24, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19489072
18.
Evaluation of 18F-IAM6067 as a sigma-1 receptor PET tracer for neurodegeneration in vivo in rodents and in human tissue.
Theranostics
; 10(18): 7938-7955, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32724451
19.
Optimization of the injected activity in dynamic 3D PET: a generalized approach using patient-specific NECs as demonstrated by a series of 15O-H2O scans.
J Nucl Med
; 50(9): 1409-17, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19690021
20.
Quantitative imaging biomarkers in the clinical development of targeted therapeutics: current and future perspectives.
Lancet Oncol
; 9(8): 766-76, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18672212