[Effect of polyethylene oxide on hemodynamic parameters in infusion therapy of irreversible hemorrhagic shock]. / Vliianie poliétilenoksida na pokazateli gemodinamiki pri infuzionnoi terapii neobratimogo gemorragicheskogo shoka.

Blood loss in 14 anesthetized cats was completely replaced either by polyglucin (control group) or polyglucin with addition of polyethylene oxide (mol. mass 6x10(6)). Blood of the cats contained 2.6-4.4 x 10(6) g/ml of polyethylene oxide. Its introduction promoted advanced recovery of hemodynamic indices and stimulated systemic oxygen transport.

[Dimethyl sulfoxide as a corrector of disorders of cerebral hemodynamics, oxygen and carbohydrate metabolism of the brain and lipid peroxidation in the early period after intracerebral hemorrhage]. / Dimetilsul'foksid kak korrektor narusheniia tserebral'noi gemo- dinamiki, kislorodnogo i uglevodnogo metabolizma mozga i lipidnoi peroksidatsii v rannie sroki posle vnutrimozgovogo krovoizliianiia.

Intraperitoneal injection of DMSO (0.7 g/kg) in rats 1h after intracerebral hemorrhage prevented brain conjugated diens and fluorosciene products increase and limited cerebral ++anti-radical activity. In experiments on cats 1h after intracerebral hemorrhage intravenous infusion of DMSO (0.3 g/kg) for 30 min improved cerebral hemodynamic, oxygen and glucose metabolism; cats mortality was decreased.

Relationship between rheological and hemodynamic changes in rats with crush syndrome.

Narcotized rats with crush syndrome develop severe syndrome of increased blood viscosity. A strict correlation was found between changes in blood viscosity at different shear rates and total peripheral vascular resistance. The severity of central hemodynamic and hemorheological disturbances was different in rats with different reaction of total peripheral vascular resistance to injury accompanied by shock.