Detalhe da pesquisa
1.
Effect of renal function on the pharmacokinetics of LCZ696 (sacubitril/valsartan), an angiotensin receptor neprilysin inhibitor.
Eur J Clin Pharmacol
; 72(9): 1065-73, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27230850
2.
Evaluation of food effect on the oral bioavailability of pradigastat, a diacylglycerol acyltransferase 1 inhibitor.
Biopharm Drug Dispos
; 36(7): 452-61, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25963481
3.
Effect of clopidogrel on the steady-state pharmacokinetics of fluvastatin.
J Clin Pharmacol
; 47(5): 613-9, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17442686
4.
Single periocular injection of celecoxib-PLGA microparticles inhibits diabetes-induced elevations in retinal PGE2, VEGF, and vascular leakage.
Invest Ophthalmol Vis Sci
; 47(3): 1149-60, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16505053
5.
Subconjunctivally administered celecoxib-PLGA microparticles sustain retinal drug levels and alleviate diabetes-induced oxidative stress in a rat model.
Eur J Pharmacol
; 511(2-3): 191-8, 2005 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-15792788
6.
Intratracheal budesonide-poly(lactide-co-glycolide) microparticles reduce oxidative stress, VEGF expression, and vascular leakage in a benzo(a)pyrene-fed mouse model.
J Pharm Pharmacol
; 57(7): 851-60, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15969944
7.
Subconjunctival nano- and microparticles sustain retinal delivery of budesonide, a corticosteroid capable of inhibiting VEGF expression.
Invest Ophthalmol Vis Sci
; 44(3): 1192-201, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12601049
8.
Induction of vascular endothelial growth factor by 4-hydroxynonenal and its prevention by glutathione precursors in retinal pigment epithelial cells.
Eur J Pharmacol
; 449(3): 213-20, 2002 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-12167462
9.
Celecoxib, a selective cyclooxygenase-2 inhibitor, inhibits retinal vascular endothelial growth factor expression and vascular leakage in a streptozotocin-induced diabetic rat model.
Eur J Pharmacol
; 458(3): 283-9, 2003 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-12504784
10.
Inhibition of cyclooxygenase-2, but not cyclooxygenase-1, reduces prostaglandin E2 secretion from diabetic rat retinas.
Eur J Pharmacol
; 498(1-3): 275-8, 2004 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-15364005
11.
Nanoparticle formulation enhances the delivery and activity of a vascular endothelial growth factor antisense oligonucleotide in human retinal pigment epithelial cells.
J Pharm Pharmacol
; 55(9): 1199-206, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-14604462
12.
Systemic and ocular pharmacokinetics of N-4-benzoylaminophenylsulfonylglycine (BAPSG), a novel aldose reductase inhibitor.
J Pharm Pharmacol
; 56(3): 351-8, 2004 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15025860
13.
Probenecid treatment enhances retinal and brain delivery of N-4-benzoylaminophenylsulfonylglycine: an anionic aldose reductase inhibitor.
Brain Res Bull
; 81(2-3): 327-32, 2010 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19761819
14.
Fluocinolone inhibits VEGF expression via glucocorticoid receptor in human retinal pigment epithelial (ARPE-19) cells and TNF-alpha-induced angiogenesis in chick chorioallantoic membrane (CAM).
J Ocul Pharmacol Ther
; 25(2): 97-103, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19284324
15.
Evaluation of the potential for steady-state pharmacokinetic interaction between vildagliptin and simvastatin in healthy subjects.
Curr Med Res Opin
; 23(12): 2913-20, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17931461
16.
Retinal delivery of celecoxib is several-fold higher following subconjunctival administration compared to systemic administration.
Pharm Res
; 21(10): 1797-804, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15553225
17.
A biodegradable injectable implant sustains systemic and ocular delivery of an aldose reductase inhibitor and ameliorates biochemical changes in a galactose-fed rat model for diabetic complications.
Pharm Res
; 19(3): 278-85, 2002 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-11934234