Detalhe da pesquisa
1.
Imidazo[2,1-b]thiazoles: multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases.
Bioorg Med Chem Lett
; 20(8): 2452-5, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20346655
2.
Development of multitargeted inhibitors of both the insulin-like growth factor receptor (IGF-IR) and members of the epidermal growth factor family of receptor tyrosine kinases.
Bioorg Med Chem Lett
; 19(6): 1718-21, 2009 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19217287
3.
Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding.
J Med Chem
; 49(13): 3832-49, 2006 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-16789740
4.
Insulin-like growth factor-1 receptor and ErbB kinase inhibitor combinations block proliferation and induce apoptosis through cyclin D1 reduction and Bax activation.
J Biol Chem
; 283(35): 23721-30, 2008 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-18559346
5.
Pyrazolo[3,4-d]pyrimidines as potent inhibitors of the insulin-like growth factor receptor (IGF-IR).
Bioorg Med Chem Lett
; 17(19): 5406-9, 2007 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17689078
6.
Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties.
Bioorg Med Chem Lett
; 16(13): 3574-7, 2006 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16632353
7.
3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.
Bioorg Med Chem Lett
; 14(4): 865-8, 2004 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-15012983