Digitizing U.S. Air Force Medical Standards for the Creation and Validation of a Readiness Decision Support System.

INTRODUCTION: Deployment-limiting medical conditions are the primary reason why service members are not medically ready. Service-specific standards guide clinicians in what conditions are restrictive for duty, fitness, and/or deployment requirements. The Air Force (AF) codifies most standards in the Medical Standards Directory (MSD). Providers manually search this document, among others, to determine if any standards are violated, a tedious and error-prone process. Digitized, standards-based decision-support tools for providers would ease this workflow. This study digitized and mapped all AF occupations to MSD occupational classes and all MSD standards to diagnosis codes and created and validated a readiness decision support system (RDSS) around this mapping. MATERIALS AND METHODS: A medical coder mapped all standards within the May 2018 v2 MSD to 2018 International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes. For the publication of new MSDs, we devised an automated update process using Amazon Web Service's Comprehend Medical and the Unified Medical Language System's Metathesaurus. We mapped Air Force Specialty Codes to occupational classes using the MSD and AF classification directories. We uploaded this mapping to a cloud-based MySQL (v5.7.23) database and built a web application to interface with it using R (v3.5+). For validation, we compared the RDSS to the record review of two subject-matter experts (SMEs) for 200 outpatient encounters in calendar year 2018. We performed four separate analyses: (1) SME vs. RDSS for any restriction; (2) SME interrater reliability for any restriction; (3) SME vs. RDSS for specific restriction(s); and (4) SME interrater reliability for categorical restriction(s). This study was approved as "Not Human Subjects Research" by the Air Force Research Laboratory (FWR20190100N) and Boston Children's Hospital (IRB-P00031397) review boards. RESULTS: Of the 709 current medical standards in the September 2019 MSD, 631 (89.0%) were mapped to ICD-10-CM codes. These 631 standards mapped to 42,810 unique ICD codes (59.5% of all active 2019 codes) and covered 72.3% (7,823/10,821) of the diagnoses listed on AF profiles and 92.8% of profile days (90.7/97.8 million) between February 1, 2007 and January 31, 2017. The RDSS identified diagnoses warranting any restrictions with 90.8% and 90.0% sensitivity compared to SME A and B. For specific restrictions, the sensitivity was 85.0% and 44.8%. The specificity was poor for any restrictions (20.5%-43.4%) and near perfect for specific restrictions (99.5+%). The interrater reliability between SMEs for all comparisons ranged from minimal to moderate (κ = 0.33-0.61). CONCLUSION: This study demonstrated key pilot steps to digitizing and mapping AF readiness standards to existing terminologies. The RDSS showed one potential application. The sensitivity between the SMEs and RDSS demonstrated its viability as a screening tool with further refinement and study. However, its performance was not evenly distributed by special duty status or for the indication of specific restrictions. With machine consumable medical standards integrated within existing digital infrastructure and clinical workflows, RDSSs would remove a significant administrative burden from providers and likely improve the accuracy of readiness metrics.

Irritable bowel syndrome: a "mesh" of a situation.

The diagnosis of irritable bowel syndrome (IBS) frequently is made after the exclusion of a mechanical etiology for a patient's symptoms. This case demonstrates that IBS symptoms can be caused by a rare complication of a common surgery: mesh herniorrhaphy repair. The patient is a 50-year-old woman who underwent periumbilical Marlex mesh herniorrhaphy 13 years before presentation. After her operation, the patient developed constipation (approximately one bowel movement per week) alternating with diarrhea for approximately 10 years. An abdominal radiograph showed large amounts of stool, and after a normal colonoscopy the patient was diagnosed with IBS. The patient was treated with tegaserod (Zelnorm) and polyethylene glycol (MiraLAX), which did not palliate her symptoms. The patient presented with obstructive symptoms and physical findings of an incarcerated umbilical hernia. A computed tomography (CT) scan of the abdomen confirmed an umbilical hernia involving a segment of small bowel with surrounding fecalization of enteric contents. During operative repair, the patient was found to have Marlex mesh fully eroded into the lumen of the small bowel, causing a partial obstruction. The involved section of small bowel was resected, and during serial follow-up the patient had complete resolution of her IBS-like symptoms. A discussion follows regarding the implications of mesh migration, and questions are posed for future research.

A "needling" problem: shoulder injury related to vaccine administration.

A 22-year-old woman with no significant medical history developed acute left shoulder pain and severe restrictions in range of motion after a seasonal influenza vaccine injection. Imaging by MRI, approximately 8 weeks after the injection, and by ultrasound, approximately 9.5 weeks after the injection demonstrated contusions on the humerus, injury of the supraspinatus, and effusion in the subacromial bursa. Her reaction was reported to the Vaccine Adverse Event Reporting System as a case of shoulder injury related to vaccine administration, likely due to injection of the influenza vaccine into the subacromial bursa. This case serves as a catalyst for discussion regarding vaccination technique and the potential to prevent complications arising from vaccine overpenetration.