[Severe Caffeine Intentional Intoxication and Delayed Elimination: a Case Report]. / Intoxication volontaire grave à la caféine et retard d'élimination : à propos d'un cas clinique.

We report a massive intoxication by caffeine (20 g) with positive clinical evolution despite potentially lethal plasma concentrations (244 µg/mL) and delayed elimination.

Improving the identification of anaerobes in the clinical microbiology laboratory through MALDI-TOF mass spectrometry.

In this study, 1325 anaerobes were analyzed by MALDI-TOF MS. Of these, 92.5% were correctly identified at the species level. One unidentified species and several uncommon and rare species were identified. These results show that this technique has become the new gold standard for the routine identification of clinical anaerobes.

[Pharmacogenetics for patient care in France: A discipline that evolves!] / La pharmacogénétique au service du soin en France : une discipline qui évolue !

Pharmacogenetics, which concepts are known for a long time, is entering a new period at least as far as its practical applications for patients are concerned. In recent years there have been more and more initiatives to promote widespread dissemination, and health authorities are increasingly incorporating these concepts into drug labels. In France, the national network of pharmacogenetics (RNPGx) works to promote these activities, both with health actors (biologists, clinicians) and health authorities. This article reviews the current situation in France and the milestones of the year 2018. It highlights recent advances in this field, in terms of currently recommended analyses, sharing of information or technological developments, and the prospects for future developments in the near future from targeted pharmacogenetics to eventually preemptive approaches.