Detalhe da pesquisa
1.
14-3-3 Proteins Reduce Cell-to-Cell Transfer and Propagation of Pathogenic α-Synuclein.
J Neurosci
; 38(38): 8211-8232, 2018 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30093536
2.
Biochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson's Disease Reveals Distinct Metabolic Profiles.
J Proteome Res
; 17(7): 2460-2469, 2018 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29762036
3.
Developmental origins of Parkinson's disease risk: perinatal exposure to the organochlorine pesticide dieldrin leads to sex-specific DNA modifications in critical neurodevelopmental pathways in the mouse midbrain.
bioRxiv
; 2024 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38746441
4.
Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology.
Nat Commun
; 15(1): 2642, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38531900
5.
Hippocampal subfield vulnerability to α-synuclein pathology precedes neurodegeneration and cognitive dysfunction.
bioRxiv
; 2023 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37090590
6.
Hippocampal subfield vulnerability to α-synuclein pathology precedes neurodegeneration and cognitive dysfunction.
NPJ Parkinsons Dis
; 9(1): 125, 2023 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37640722
7.
Spatial transcriptomics reveals molecular dysfunction associated with Lewy pathology.
bioRxiv
; 2023 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292685
8.
Air pollution nanoparticle and alpha-synuclein fibrils synergistically decrease glutamate receptor A1, depending upon nPM batch activity.
Heliyon
; 9(4): e15622, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37128335
9.
An extended release GLP-1 analogue increases α-synuclein accumulation in a mouse model of prodromal Parkinson's disease.
Exp Neurol
; 341: 113693, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33727096
10.
T Cells Limit Accumulation of Aggregate Pathology Following Intrastriatal Injection of α-Synuclein Fibrils.
J Parkinsons Dis
; 11(2): 585-603, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33579871
11.
Modeling α-Synucleinopathy in Organotypic Brain Slice Culture with Preformed α-Synuclein Amyloid Fibrils.
J Parkinsons Dis
; 10(4): 1397-1410, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32716318
12.
Inhibiting the mitochondrial pyruvate carrier does not ameliorate synucleinopathy in the absence of inflammation or metabolic deficits.
Free Neuropathol
; 12020.
Artigo
em Inglês
| MEDLINE | ID: mdl-35224554
13.
Skin α-Synuclein Aggregation Seeding Activity as a Novel Biomarker for Parkinson Disease.
JAMA Neurol
; 2020 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32986090
14.
Pathogenic alpha-synuclein aggregates preferentially bind to mitochondria and affect cellular respiration.
Acta Neuropathol Commun
; 7(1): 41, 2019 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30871620
15.
Loss of One Engrailed1 Allele Enhances Induced α-Synucleinopathy.
J Parkinsons Dis
; 9(2): 315-326, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30932894
16.
Detecting Alpha Synuclein Seeding Activity in Formaldehyde-Fixed MSA Patient Tissue by PMCA.
Mol Neurobiol
; 55(11): 8728-8737, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29589283
17.
Metabolomic Profiling of Bile Acids in an Experimental Model of Prodromal Parkinson's Disease.
Metabolites
; 8(4)2018 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30384419